Apply for Xenazine (Tetrabenazine) Copay Assistance Now

Tetrabenazine (Xenazine) is FDA-approved to treat chorea associated with Huntington’s disease in the United States. Chorea refers to the involuntary, irregular movements that are one of the hallmark symptoms of Huntington’s disease.

Tetrabenazine is also used off-label for tardive dyskinesia, a movement disorder caused by long-term use of certain psychiatric medications. In Canada, it is additionally approved for chronic tic disorders including Tourette syndrome.

Tetrabenazine is available in two tablet strengths:

• 12.5 mg tablets
• 25 mg tablets

Your doctor will determine the appropriate starting dose and may gradually adjust it over several weeks based on your individual response and tolerability. If you have questions about your specific prescription, call our pharmacists at (917) 830-2525 — we’re available 24/7.

Tetrabenazine is taken orally with or without food. Dosing is individualized and adjusted gradually under a physician’s supervision:

• Typical starting dose: 12.5 mg once daily in the morning
• May be increased to 12.5 mg twice daily after one week
• Further increases of 12.5 mg may be made at weekly intervals up to 50 mg/day
• Doses greater than 37.5 mg/day are divided into three daily doses, with no single dose exceeding 25 mg

Always follow your physician’s instructions exactly. Never adjust your dose without first consulting your doctor.

Common side effects of tetrabenazine (reported in more than 10% of patients) include:

• Drowsiness and sedation
• Fatigue and loss of energy
• Insomnia
• Nausea
• Akathisia (restlessness or an uncontrollable urge to move)
• Depression and anxiety
• Extrapyramidal symptoms such as parkinsonism (slow movement, muscle stiffness)
• Falling
• Upper respiratory tract infections

Important: Tetrabenazine carries an FDA Boxed Warning for an increased risk of depression and suicidal thoughts and behavior in patients with Huntington’s disease. Contact your physician immediately if you experience mood changes, worsening depression, or thoughts of self-harm.

Yes. Tetrabenazine is contraindicated (should not be used) in patients who:

• Are actively suicidal
• Have untreated or inadequately treated depression
• Have hepatic (liver) impairment
• Are currently taking monoamine oxidase inhibitors (MAOIs) or have taken them within the past 2 weeks
• Are currently taking reserpine (at least 20 days should pass after stopping reserpine before starting tetrabenazine)
• Are currently taking deutetrabenazine or valbenazine

Always inform your doctor about all medications, supplements, and medical conditions before starting tetrabenazine.

If you miss a dose, take it as soon as you remember. However, if it is close to the time of your next scheduled dose, skip the missed dose and continue your regular schedule. Do not double up on doses.

If you miss doses for more than 5 consecutive days, consult your doctor before restarting. Retitration (starting over at a lower dose) is typically recommended after an interruption of more than 5 days.

Tetrabenazine may be discontinued without tapering. However, chorea symptoms may return within 12 to 18 hours after the last dose as the medication clears your system. Always consult your physician before making any changes to your medication regimen.

You may qualify for QuickRx’s tetrabenazine copay assistance program if:

• You are receiving treatment in the United States
• Your insurance is covering a portion of your medication cost
• You are diagnosed and being treated for a qualifying movement disorder, including:
  • Huntington’s disease-associated chorea
  • Tardive dyskinesia
  • Tourette syndrome

Not sure if you qualify? Call us at (917) 830-2525 and we’ll help determine your eligibility at no cost to you.

QuickRx Specialty Pharmacy accepts most major commercial insurance plans and works with patients across all 50 states. Our patient navigator team will verify your coverage and benefits as part of the copay assistance enrollment process — at no cost to you.

Yes. QuickRx can help connect uninsured patients with manufacturer patient assistance programs that may provide tetrabenazine at low or no cost for those who qualify based on income and other criteria. Call our patient navigator team at (917) 830-2525 to discuss your options.

Applying is simple. You can:

• Fill out the inquiry form on this page
• Call our patient navigator team at (917) 830-2525 — available 24/7
• Email us at info@quickrxspecialty.com

A QuickRx patient navigator will contact you within 24 hours to begin the enrollment process.

No. QuickRx’s patient navigation and copay assistance enrollment services are completely free for patients. We are paid by the pharmacy — never by you.

Timelines vary depending on the type of assistance and your insurance situation. Our team works as quickly as possible and will keep you informed at every step. In many cases, we are able to have assistance confirmed before your first refill is needed. Contact us early — the sooner we start, the better.

Yes. QuickRx Specialty Pharmacy is licensed in all 50 states and ships tetrabenazine directly to patients’ homes with free nationwide delivery. We handle all packaging and shipping logistics, including any temperature or handling requirements specific to your medication.