Apply for Pomalyst (Pomalidomide) Copay Card & Copay Assistance Now.

Pomalyst (pomalidomide) is an immunomodulatory drug used to treat multiple myeloma, a type of blood cancer that affects plasma cells in the bone marrow. According to National Cancer Institute information, Pomalyst is FDA-approved for:

• Multiple myeloma in combination with dexamethasone in patients who have received at least two prior therapies including lenalidomide and a proteasome inhibitor and have demonstrated disease progression on or within 60 days of completion of the last therapy
• AIDS-related Kaposi sarcoma in patients whose disease has not improved after highly active antiretroviral therapy (HAART) or in HIV-negative patients

QuickRx Specialty Pharmacy dispenses Pomalyst and coordinates copay assistance to help multiple myeloma patients afford their treatment.

Pomalyst (pomalidomide) is an immunomodulatory agent with multiple mechanisms of action against multiple myeloma:

• Direct anti-tumor effects: Induces apoptosis (programmed cell death) in myeloma cells
• Immune system activation: Stimulates T cells and natural killer (NK) cells to attack cancer cells
• Anti-angiogenic effects: Inhibits the growth of new blood vessels that tumors need to grow
• Microenvironment disruption: Interferes with the bone marrow environment that supports myeloma cell survival

Pomalidomide is structurally similar to thalidomide and lenalidomide but has enhanced potency and may be effective in patients who have become resistant to other immunomodulatory drugs.

According to FDA prescribing information, the recommended starting dose of Pomalyst for multiple myeloma is:

• 4 mg taken orally once daily on Days 1-21 of repeated 28-day cycles
• Taken with dexamethasone (40 mg daily on Days 1, 8, 15, and 22 for patients ≤75 years; 20 mg for patients >75 years)
• Continue treatment until disease progression or unacceptable toxicity

For AIDS-related Kaposi sarcoma, the recommended dose is 5 mg once daily on Days 1-21 of 28-day cycles until disease progression or unacceptable toxicity.

Your oncologist will determine the appropriate dose based on your specific situation and may adjust it based on side effects or response to treatment.

For optimal results and safety, follow these important guidelines:

• Take at the same time each day: Consistency helps maintain steady drug levels
• Take with or without food: Pomalyst can be taken regardless of meals
• Swallow capsules whole: Do not break, chew, or open the capsules
• Handle carefully: Pomalyst capsules should not be handled by pregnant women or those who may become pregnant
• If you miss a dose: Take it as soon as you remember if within 12 hours; otherwise skip and take the next dose at the regular time
• Do not take two doses at once

Your QuickRx pharmacist can provide personalized guidance on incorporating Pomalyst into your treatment routine.

Like all chemotherapy medications, Pomalyst can cause side effects. Understanding what to expect helps you work with your healthcare team to manage them effectively.

Very common side effects (occurring in more than 10% of patients):

Blood-related:

• Neutropenia (low white blood cells) – 50% to 52%
• Anemia (low red blood cells) – 38%
• Thrombocytopenia (low platelets) – 25%
• Leukopenia (low white blood cells) – 11%

General:

• Fatigue and weakness – 28% to 55%
• Fever – 19% to 27%
• Edema (swelling) – 14% to 23%

Gastrointestinal:

• Constipation – 22% to 36%
• Diarrhea – 21% to 34%
• Nausea – 15% to 36%
• Decreased appetite – 17% to 22%

Other common effects:

• Back pain – 12% to 32%
• Muscle spasms – 19% to 22%
• Upper respiratory infection – 10% to 32%
• Peripheral neuropathy (numbness/tingling) – 10% to 18%
• Dizziness – 14% to 20%

Contact your healthcare provider immediately or seek emergency care if you experience:

Blood Clots (Venous Thromboembolism):

• Deep vein thrombosis (DVT): leg swelling, pain, warmth, or redness
• Pulmonary embolism (PE): sudden shortness of breath, chest pain, rapid heartbeat
• Stroke symptoms: sudden confusion, trouble speaking, weakness on one side

Severe Allergic Reactions:

• Severe skin reactions (Stevens-Johnson syndrome)
• Angioedema (swelling of face, lips, tongue, throat)
• Anaphylaxis

Serious Infections:

• Fever above 100.4°F (38°C)
• Chills or shaking
• Persistent cough or breathing problems
• Signs of pneumonia or sepsis

Liver Problems:

• Yellowing of skin or eyes (jaundice)
• Dark urine
• Severe fatigue
• Upper right abdominal pain

Other Serious Effects:

• Tumor lysis syndrome (rapid breakdown of cancer cells)
• Second primary malignancies (new cancers)
• Severe neuropathy

Pomalyst is only available through a restricted program called Pomalyst REMS® (Risk Evaluation and Mitigation Strategy) due to the risk of serious birth defects. According to FDA REMS requirements:

Requirements for patients:

• Must be enrolled in the Pomalyst REMS program before receiving medication
• Females of reproductive potential must have two negative pregnancy tests before starting
• Must use two forms of effective contraception or abstain from heterosexual sex
• Must not donate blood or sperm during treatment and for specified time after
• Must comply with regular pregnancy testing (females)

QuickRx helps with REMS enrollment:
Our pharmacy is certified under the Pomalyst REMS program. We coordinate all REMS requirements alongside your copay assistance enrollment, ensuring seamless access to your medication.

Pomalyst can interact with several medications. Important interactions include:

CYP1A2 Inhibitors (may increase pomalidomide levels):

• Fluvoxamine
• Ciprofloxacin
• Enoxacin

Strong CYP1A2 Inducers (may decrease pomalidomide levels):

• Smoking (tobacco)
• Certain medications that induce this enzyme

Medications that increase blood clot risk:

• Erythropoiesis-stimulating agents (EPO)
• Estrogen-containing products

Dexamethasone interactions:
Since Pomalyst is taken with dexamethasone, be aware of steroid interactions with:

• Blood thinners
• Diabetes medications
• Certain antibiotics and antifungals

Always inform your healthcare provider and pharmacist about ALL medications, supplements, and herbal products you take. Your QuickRx pharmacist will conduct a thorough review of your medication profile.

Patients on Pomalyst require regular monitoring:

Blood Tests:

• Complete blood count (CBC) weekly for first 8 weeks, then monthly
• Monitor for neutropenia, thrombocytopenia, and anemia
• Liver function tests periodically

Pregnancy Testing (females of reproductive potential):

• Two negative tests before starting treatment
• Weekly during first month
• Monthly thereafter
• At discontinuation and 4 weeks after

Other Monitoring:

• Signs of blood clots (DVT/PE)
• Signs of infection
• Neuropathy symptoms
• Second primary malignancies

QuickRx coordinates with your oncology team to ensure all necessary monitoring is completed.

NO. Pomalyst is contraindicated during pregnancy.

Pomalyst can cause severe, life-threatening birth defects or embryo-fetal death. According to FDA safety information:

• Females must have negative pregnancy tests before starting treatment
• Must use two effective forms of birth control or abstain completely
• Pregnancy testing continues throughout treatment
• Males must use condoms during treatment and for 4 weeks after
• Do not donate blood or sperm during treatment

If pregnancy occurs during treatment, stop Pomalyst immediately and contact your healthcare provider. There is a pregnancy exposure registry to monitor outcomes.

A Pomalyst copay card is a manufacturer-sponsored program that reduces your out-of-pocket costs at the pharmacy. These programs help make multiple myeloma treatment more affordable.

How the Pomalyst copay card works:

1. You present your copay card along with your insurance card at the pharmacy
2. Your insurance is billed first and determines your copay/coinsurance amount
3. The copay card covers the difference between your insurance copay and a lower amount
4. Eligible patients may pay $0 for their Pomalyst prescription

QuickRx handles the entire Pomalyst copay card enrollment process at no cost to you. We ensure your copay assistance is applied correctly to every fill and monitor your benefits to prevent any gaps in coverage.

Eligibility for Pomalyst copay assistance depends on your insurance type:

Commercially insured patients:

• Active commercial (private) health insurance that covers Pomalyst
• Valid prescription from a licensed oncologist
• U.S. residency
• NOT enrolled in Medicare, Medicaid, TRICARE, VA, or other government-funded programs

Medicare and Medicaid patients:

• Cannot use manufacturer copay cards due to federal Anti-Kickback regulations
• May qualify for independent foundation grants (income-based eligibility)
• QuickRx connects eligible patients to foundation programs for oncology medications

Uninsured patients:

• May qualify for manufacturer patient assistance programs providing free medication
• Income limits typically apply
• Annual application required with income documentation

QuickRx evaluates your specific situation and identifies every Pomalyst copay assistance program you qualify for.

Getting started with Pomalyst copay assistance is simple:

Step 1: Contact QuickRx
Call (917) 830-2525 or toll-free (800) 496-6111, or complete our online enrollment form above.

Step 2: Benefits Verification
A QuickRx specialist will verify your insurance benefits and identify all available Pomalyst copay card and patient assistance programs you qualify for.

Step 3: REMS & Copay Enrollment
We coordinate both your Pomalyst REMS program enrollment and copay assistance application simultaneously—no extra steps for you.

Step 4: Ongoing Support
Once enrolled, QuickRx monitors your benefits continuously, coordinates refills, arranges nationwide home delivery, and ensures you never experience a surprise lapse in coverage.

No. QuickRx provides free Pomalyst copay card and patient assistance program enrollment. We believe financial barriers shouldn’t prevent multiple myeloma patients from accessing life-saving treatment.

Our services include:

• ✓ Free benefits verification
• ✓ Free copay card enrollment
• ✓ Free patient assistance program applications
• ✓ Free REMS coordination
• ✓ Free prior authorization support
• ✓ 24/7 pharmacist access

QuickRx Specialty Pharmacy provides comprehensive support for multiple myeloma patients on complex medications like Pomalyst:

• ACHC-Accredited & URAC-Accredited: QuickRx maintains the highest standards for specialty pharmacy services
• Oncology expertise: Our pharmacists specialize in multiple myeloma and blood cancer medications
• REMS-certified pharmacy: We’re certified to dispense Pomalyst under the REMS program
• Complete copay assistance coordination: We identify and enroll you in every program you qualify for
• Insurance navigation: Prior authorization support, benefits verification, and appeals assistance
• Nationwide home delivery: Licensed in all 50 states with temperature-controlled shipping
• 24/7 pharmacist access: Questions answered any time, day or night
• Proactive refill management: We contact you before you run out of medication

Contact QuickRx today at (917) 830-2525 to learn how we can help reduce your Pomalyst costs.

References

1. U.S. Food and Drug Administration. Pomalyst (pomalidomide) Prescribing Information. Bristol-Myers Squibb.
2. National Cancer Institute. Pomalidomide Drug Information.
3. U.S. Food and Drug Administration. Risk Evaluation and Mitigation Strategies (REMS).
4. National Institutes of Health. Multiple Myeloma. StatPearls Publishing.
5. Multiple Myeloma Research Foundation. Patient Resources and Support.
6. Leukemia & Lymphoma Society. Myeloma Patient Information.
7. International Myeloma Foundation. Myeloma Education and Support.