Ofev (Nintedanib) Copay Assistance

What you pay for nintedanib depends on whether you receive brand-name Ofev or generic nintedanib, your pharmacy, your insurance, and any discounts or assistance you qualify for. Without insurance or assistance, cash prices are high, but most patients pay far less through copay cards, patient assistance programs, or foundation grants.

Generic nintedanib launched in the U.S. in 2026 and is generally priced below brand Ofev. Published cash prices vary significantly by pharmacy and discount, with the lowest advertised prices around $1,900 per month and higher retail prices at some pharmacies. Your actual cost depends on your insurance, pharmacy, dose, and assistance program.

At QuickRx, no patient should skip treatment because of cost. Depending on your coverage, you may pay as little as $0 — commercially insured patients prescribed brand Ofev may qualify for the manufacturer copay card (up to the program’s annual maximum; terms apply), and other patients may qualify for a patient assistance program or a nonprofit foundation grant. Call (917) 830-2525 to find out what you qualify for.

Pricing last reviewed July 22, 2026 and reflects published U.S. cash prices from Drugs.com and CoveredUSA. Prices vary by pharmacy, dose, region, insurance, and available discounts and are subject to change. This is not a quote or a guarantee of price or savings.

Yes, for brand-name Ofev. Eligible patients with commercial (private) insurance who are prescribed brand Ofev may pay as little as $0 per month using the manufacturer’s copay card, up to the program’s annual maximum benefit. Terms and conditions apply.

Important: the manufacturer copay card applies to brand-name Ofev only and cannot be used by patients with Medicare, Medicaid, or other government-funded insurance. If you are prescribed generic nintedanib, or you have government insurance, other savings options may still help, including patient assistance programs and nonprofit foundation grants.

QuickRx enrolls you for free and applies eligible savings when we dispense your medication. QuickRx Specialty Pharmacy does not issue or administer manufacturer copay cards; copay cards are provided by the drug manufacturer. Call (917) 830-2525 to find out if you qualify.

Ofev copay assistance helps lower your out-of-pocket cost for Ofev (nintedanib). It covers three program types: manufacturer copay cards (for commercially insured patients on brand Ofev), patient assistance programs, and nonprofit foundation grants.

QuickRx Specialty Pharmacy enrolls you for free. We review the programs you may qualify for based on your insurance and financial situation. Our patient navigators handle the paperwork so you can focus on your treatment. Eligibility depends on each program’s rules and is not guaranteed.

Each program has its own eligibility rules.

• Manufacturer copay card: For patients with commercial (private) insurance who are prescribed brand-name Ofev. Not available to patients with Medicare, Medicaid, or other government insurance.
• Nintedanib patient assistance programs: Generally serve uninsured patients, and may help patients on Medicare or Medicaid when those plans do not cover the copay benefit. Eligibility is often based on income.
• Foundation grants: Offered by independent nonprofits and often available regardless of insurance type, including Medicare, when funding is open.

Because generic nintedanib is now available, patients also have savings options outside the brand-name copay card program. QuickRx reviews your situation for free. Call (917) 830-2525 to speak with a patient navigator.

No. QuickRx Specialty Pharmacy enrolls you in copay assistance for free. No fees. No hidden charges. No obligation. Cost should never block pulmonary fibrosis treatment.

What QuickRx Does For Free:

• Reviews your insurance and identifies available programs
• Compares brand Ofev and generic nintedanib savings options
• Completes copay card and nintedanib patient assistance applications
• Coordinates with your healthcare provider for documentation
• Manages renewals and insurance changes
• Provides ongoing support throughout your treatment

Yes. Generic nintedanib launched in the United States in 2026 and is generally priced below brand-name Ofev.

Generic nintedanib contains the same active ingredient as brand Ofev, nintedanib esylate, in the same 100 mg and 150 mg capsules.

Whether you receive brand or generic nintedanib depends on your insurance formulary, your prescriber’s choice, and your clinical situation.

Keep in mind that the manufacturer copay card applies to brand Ofev only; generic savings typically come through lower pricing, patient assistance programs, or foundation grants. QuickRx patient navigators help you understand your options and find the best available savings for brand or generic. Call (917) 830-2525 for a free benefits review.

Medicare patients cannot use manufacturer copay cards. Federal regulations block this. Good news: other financial help may still be available for Ofev or generic nintedanib.

Options for Medicare Patients:

• Nintedanib patient assistance programs: May provide medication at reduced or no cost based on eligibility
• Generic nintedanib: May fall under a lower cost tier on Medicare Part D
• Pulmonary fibrosis foundation grants: Nonprofits help IPF and ILD patients regardless of insurance, when funding is open
• Medicare Extra Help / Low-Income Subsidy: Helps with specialty drug costs
• State pharmaceutical assistance programs: Varies by state

QuickRx patient navigators review your Medicare coverage and identify available options, all for free. Eligibility and funding are not guaranteed.

Ofev (nintedanib) is an oral prescription drug. The FDA approved it for three lung conditions in adults.

FDA-Approved Indications for Ofev:

• Idiopathic pulmonary fibrosis (IPF): A chronic lung disease that scars lung tissue. The cause is unknown. Ofev slows the decline of lung function in adults with IPF.
• Progressive pulmonary fibrosis (PPF): Ofev treats chronic progressive fibrosing interstitial lung diseases (ILDs). These ILDs keep getting worse despite treatment. Causes include rheumatoid arthritis, sarcoidosis, and hypersensitivity pneumonitis.
• Systemic sclerosis–associated interstitial lung disease (SSc-ILD): Ofev slows the decline of lung function in patients with ILD from systemic sclerosis (scleroderma).

Ofev does not cure these conditions. It does not reverse existing scar tissue. It works by slowing disease progression and protecting lung function.

You take Ofev (nintedanib) by mouth as a capsule. Take it twice a day, about 12 hours apart.

Ofev Dosing Information:

• Standard dose (no liver impairment): 150 mg every 12 hours with food. Maximum dose: 300 mg per day.
• Reduced dose (mild hepatic impairment, Child-Pugh A): 100 mg every 12 hours with food.
• Moderate to severe hepatic impairment: Ofev is not recommended.
• If you miss a dose, skip it. Take the next dose at the regular time. Do not double up.

Important Administration Notes:

• Swallow capsules whole with liquid. Do not open, chew, or crush. The contents taste bitter and can irritate.
• If you touch the capsule contents, wash your hands right away.
• If you smoke, stop before starting Ofev. Smoking lowers Ofev exposure by about 21%.

Follow your healthcare provider’s dosing instructions.

Diarrhea is the most common side effect of Ofev. Most patients get it. GI side effects are usually mild to moderate. They happen most often in the first 3 months of treatment.

Common Ofev Side Effects (>10%):

• Diarrhea (62% to 76% of patients), the most frequent side effect
• Nausea (24% to 32%)
• Vomiting (12% to 25%)
• Abdominal pain (15% to 18%)
• Decreased appetite (9% to 11%)
• Weight loss (10% to 12%)
• Increased liver enzymes (13% to 14%)
• Fatigue (10% to 11%)
• Nasopharyngitis (13%)

Many patients keep loperamide (Imodium) on hand for diarrhea. Drink plenty of water. Talk to your healthcare provider about any side effect that worries you.

Yes. Ofev has important warnings. Discuss them with your prescriber before and during treatment.

Important Ofev Warnings:

• Liver toxicity: Serious liver injury can happen. Some cases have been fatal. You will need liver function tests (ALT, AST, bilirubin) before you start Ofev and during the first 3 months. Risk is higher in women, patients under 65 kg, Asian patients, and older patients.
• Diarrhea: Severe diarrhea can cause life-threatening dehydration. Call your doctor right away if it is severe or won’t stop.
• Bleeding: Ofev can raise the risk of serious bleeding. Use with care if you have a bleeding risk or take anticoagulants.
• Arterial thromboembolic events: Heart attacks can happen. Use with care if you have cardiovascular risk factors.
• GI perforation: Rare cases of gastrointestinal perforation can happen. Some have been fatal. Use with care after abdominal surgery, with diverticular disease, or with NSAIDs or corticosteroids.
• Fetal harm: Ofev can cause birth defects or fetal death. Patients who can get pregnant must use highly effective birth control during treatment and for 3 months after the last dose.

This information is for learning only. Review all risks with your prescriber before starting Ofev.

Store Ofev capsules at room temperature.

Ofev Storage Instructions:

• Keep at 68°F to 77°F (20°C to 25°C)
• Brief shifts between 59°F and 86°F (15°C and 30°C) are okay
• Protect from high humidity
• Avoid heat
• Keep in the original container

Questions about storing your Ofev? Call your QuickRx pharmacist at (917) 830-2525.

IPF is a chronic lung disease. Scar tissue (fibrosis) builds up in the lungs. The cause is unknown. “Idiopathic” means the origin is unknown.

As lungs scar, they get stiffer. They cannot move oxygen into the bloodstream as well. Patients feel more breathless over time.

Key Facts About IPF:

• IPF mostly affects adults over 60
• It is more common in men and people with a smoking history
• There is no cure for IPF. Treatment focuses on slowing the disease
• Ofev (nintedanib) and pirfenidone are the two FDA-approved drugs that slow lung function decline in IPF
• Symptoms include shortness of breath, dry cough, fatigue, and a crackling sound in the lungs when you breathe

If you have IPF, work with a pulmonologist who specializes in interstitial lung diseases.

PPF describes a pattern of disease behavior. It is not one specific condition.

In PPF, scarring keeps getting worse despite treatment. This happens in chronic fibrosing interstitial lung diseases (ILDs) no matter the underlying cause.

Unlike IPF, PPF has a known cause. It can show up with rheumatoid arthritis, sarcoidosis, hypersensitivity pneumonitis, mixed connective tissue disease, and other inflammatory conditions.

When these ILDs keep getting worse and don’t respond to standard treatment, Ofev slows further lung function decline. A pulmonologist manages PPF, often working with a rheumatologist or another specialist.

SSc-ILD is a lung complication of systemic sclerosis (scleroderma). Systemic sclerosis is a rare autoimmune disease. It hardens the skin and connective tissues.

When systemic sclerosis affects the lungs, it scars and inflames lung tissue (ILD). This makes breathing harder over time.

SSc-ILD is one of the top causes of illness and death in systemic sclerosis patients. Ofev slows the decline of lung function in SSc-ILD. A rheumatologist and pulmonologist both manage this condition.

Do you have systemic sclerosis and take Ofev? QuickRx patient navigators help you find Ofev copay assistance options. Call (917) 830-2525.

Yes. Ofev (nintedanib) has important drug interactions. Tell your healthcare provider and pharmacist about all medications, supplements, and herbal products you take.

Notable Ofev Drug Interactions:

• Anticoagulants (blood thinners): Can raise bleeding risk. Monitor closely.
• Strong CYP3A4 and P-glycoprotein inducers (rifampin, St. John’s wort): Lower Ofev blood levels and reduce its effect. Avoid.
• Strong CYP3A4 and P-glycoprotein inhibitors: Raise Ofev blood levels and worsen side effects. Monitor closely.
• NSAIDs (ibuprofen, naproxen, aspirin): Can raise bleeding risk with Ofev. Ask your doctor first.
• Tobacco (smoking): Lowers Ofev exposure by about 21%. Stop smoking before and during Ofev therapy.
• Letrozole: Can raise Ofev blood levels. Monitor for side effects.

QuickRx pharmacists review all drug interactions when we dispense your Ofev. Call (917) 830-2525 with any questions.

Yes. QuickRx Specialty Pharmacy ships brand Ofev and generic nintedanib to all 50 states. Free home delivery. Proper shipping to keep your medication safe.

Why Patients Choose QuickRx for Ofev:

• Free copay assistance enrollment support for brand and generic nintedanib
• Dedicated patient navigators for IPF, PPF, and SSc-ILD patients
• Prior authorization support and appeals
• URAC- and ACHC-accredited specialty pharmacy
• One-on-one support from enrollment through your treatment

Call (917) 830-2525 or fill out the form on this page to get started.

QuickRx is a URAC- and ACHC-accredited specialty pharmacy. Our patient navigator team gives you hands-on financial support for your nintedanib treatment.

What Sets QuickRx Apart:

• Patient navigators trained in pulmonary fibrosis, rare lung disease, and autoimmune conditions
• Savings options for brand Ofev and generic nintedanib
• Free enrollment support for copay cards, patient assistance programs, and foundation grants
• Prior authorization and appeals support
• Licensed in all 50 states with free home delivery
• URAC- and ACHC-accredited, the highest standards in specialty pharmacy

No patient with IPF, PPF, or SSc-ILD should go without treatment due to cost. Fill out the form above or call (917) 830-2525 today.

This page is for education only. It is not medical advice. Ofev (nintedanib) does not cure idiopathic pulmonary fibrosis, progressive pulmonary fibrosis, or systemic sclerosis–associated interstitial lung disease.

Copay assistance and program eligibility depend on your insurance, income, prescriber, and other factors. Programs and funding can change or close at any time. QuickRx Specialty Pharmacy does not issue or administer manufacturer copay cards and does not guarantee enrollment, savings, or a specific price in any program. Manufacturer copay cards are for eligible commercially insured patients only and cannot be used with Medicare, Medicaid, or other government-funded insurance.

Pricing shown on this page was last reviewed July 22, 2026 and reflects published U.S. cash prices, which vary by pharmacy, dose, region, insurance, and available discounts and are subject to change.

Talk to your healthcare provider about your treatment plan. If you are pregnant or may become pregnant, talk to your prescriber about the fetal risk of nintedanib before you start therapy.

1. Ofev (nintedanib) [prescribing information]. Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals Inc; May 2025.
2. Pulmonary Fibrosis Foundation. About pulmonary fibrosis. Available at: pulmonaryfibrosis.org
3. American Lung Association. Idiopathic pulmonary fibrosis. Available at: lung.org
4. Richeldi L, du Bois RM, Raghu G, et al; INPULSIS Trial Investigators. Efficacy and safety of nintedanib in idiopathic pulmonary fibrosis. N Engl J Med. 2014;370(22):2071–2082. PubMed: 24836310
5. Flaherty KR, Wells AU, Cottin V, et al; INBUILD Trial Investigators. Nintedanib in progressive fibrosing interstitial lung diseases. N Engl J Med. 2019;381(18):1718–1727. PubMed: 31566307
6. Distler O, Highland KB, Gahlemann M, et al; SENSCIS Trial Investigators. Nintedanib for systemic sclerosis–associated interstitial lung disease. N Engl J Med. 2019;380(26):2518–2528. PubMed: 31112379
7. US Food and Drug Administration. Ofev prescribing information. Available at: FDA.gov
8. Drugs.com. Nintedanib prices, coupons and patient assistance. Available at: drugs.com (accessed July 22, 2026).
9. Drugs.com. Generic Ofev availability. Available at: drugs.com (accessed July 22, 2026).

Written by: Paola Larrabure, Pharma Content Manager at QuickRx Specialty Pharmacy. Paola creates patient-focused content on specialty medications, copay assistance, and rare disease support.

Medically reviewed by: Julia Kravtsova, PharmD, Head Patient Navigator at QuickRx Specialty Pharmacy. Julia is a licensed pharmacist. She reviews all clinical content on this site for accuracy. Her work focuses on patient navigation across oncology, autoimmune disease, rare disease, and pulmonary conditions.

Last Updated: July 22, 2026