Apply for Afinitor or Zortress (Everolimus) Copay Assistance| QuickRx

Without insurance or copay assistance, Afinitor (everolimus) can cost over $15,000 per month depending on your prescribed dose and pharmacy. This high cost puts significant financial strain on patients fighting cancer or managing tuberous sclerosis complex (TSC). However, eligible patients may pay as little as $0 through copay assistance programs.

Why is Afinitor so expensive?

Afinitor is a specialty medication that requires extensive research, development, and manufacturing processes. As an mTOR inhibitor used to treat multiple serious conditions including advanced breast cancer, renal cell carcinoma, neuroendocrine tumors, and TSC-related conditions, Afinitor represents cutting-edge oncology treatment. The price reflects the complexity of producing targeted cancer therapies.

How QuickRx helps reduce your Afinitor costs:

• Manufacturer copay cards: The Novartis Universal Co-Pay Card can reduce costs to $0 for eligible commercially insured patients
• Patient assistance programs: The Novartis Patient Assistance Foundation provides free Afinitor to qualifying uninsured patients
• Foundation grants: Cancer-specific foundations may provide additional financial support
• Generic alternatives: Generic everolimus may be available at lower cost for some indications

QuickRx provides all copay assistance services completely free of charge. Call (917) 830-2525 to find out how much you could save on Afinitor.

Yes, generic everolimus is available for certain indications, which may offer significant cost savings compared to brand-name Afinitor. Generic medications contain the same active ingredient and work the same way as the brand-name version but typically cost less.

Generic everolimus availability:

Generic everolimus tablets are available in multiple strengths (2.5 mg, 5 mg, 7.5 mg, and 10 mg) from several manufacturers. However, availability may vary depending on your specific indication and insurance coverage. Your oncologist and pharmacist can help determine if generic everolimus is appropriate for your condition. Learn more about generic drugs from the FDA.

Afinitor vs generic everolimus:

• Same active ingredient: Generic everolimus contains the identical active compound as Afinitor
• FDA-approved: Generic versions must meet the same safety and efficacy standards
• Potential cost savings: Generic medications often cost significantly less than brand-name options
• Copay assistance available: QuickRx can help find copay assistance for both brand and generic versions

How QuickRx helps with generic everolimus:

QuickRx can help determine if generic everolimus is appropriate for your condition and identify copay assistance options for either brand or generic versions. In many cases, combining generic pricing with copay assistance results in the lowest possible out-of-pocket cost. Call (917) 830-2525 to discuss your options.

Afinitor (everolimus) is FDA-approved to treat several types of cancer and conditions related to tuberous sclerosis complex (TSC). As an mTOR inhibitor, Afinitor works by blocking a protein that helps cancer cells grow and divide.

FDA-approved indications for Afinitor:

Cancer indications:

• Advanced HR+, HER2-negative breast cancer: Used in combination with exemestane in postmenopausal women after failure of letrozole or anastrozole treatment. Learn more about hormone receptor-positive breast cancer.
• Progressive neuroendocrine tumors of pancreatic origin (PNET): For unresectable, locally advanced, or metastatic disease. Learn more about pancreatic neuroendocrine tumors.
• Progressive neuroendocrine tumors (NET) of GI or lung origin: For well-differentiated, non-functional tumors that are unresectable, locally advanced, or metastatic
• Advanced renal cell carcinoma (RCC): After failure of treatment with sunitinib or sorafenib. Learn more about kidney cancer.

Tuberous sclerosis complex (TSC) indications:

• Renal angiomyolipoma with TSC: For patients not requiring immediate surgery
• Subependymal giant cell astrocytoma (SEGA) with TSC: For patients who require treatment but cannot have the tumor surgically removed. Learn more about tuberous sclerosis complex from the NIH.

Note: Afinitor is NOT indicated for functional carcinoid tumors. QuickRx provides copay assistance for all FDA-approved Afinitor indications.

Afinitor is typically taken as a 10 mg tablet once daily by mouth. Following proper administration guidelines is essential for treatment effectiveness and safety.

Afinitor dosing and administration:

• Standard dose: 10 mg once daily for most cancer indications
• Swallow tablets whole: Do not crush, chew, or break Afinitor tablets
• With or without food: Take consistently the same way each day
• Same time daily: Taking Afinitor at the same time helps maintain steady drug levels
• If you miss a dose: Take it if within 6 hours of your regular time; otherwise, skip and take the next dose at your regular time

Important dietary restrictions with Afinitor:

Avoid grapefruit and grapefruit juice while taking Afinitor. Grapefruit can increase everolimus levels in your body, potentially increasing side effects. Also avoid Seville oranges, pomelos, and other citrus fruits that may interact with the medication. Learn more about grapefruit and drug interactions from the FDA.

Afinitor Disperz (tablet for oral suspension):

For patients who cannot swallow tablets, Afinitor Disperz is available as a tablet that can be dispersed in water before taking. This formulation is prepared differently—follow your pharmacist’s specific instructions for preparation.

QuickRx pharmacists are available to answer questions about taking Afinitor correctly. Call (917) 830-2525.

No, QuickRx copay assistance services are always 100% FREE to patients. We never charge for helping you enroll in manufacturer copay cards, patient assistance programs, or foundation grants for Afinitor (everolimus).

What’s included at no cost:

• Program identification: We research all available Afinitor copay assistance options
• Application support: We complete paperwork and submit applications on your behalf
• Insurance verification: We check your benefits and coverage details
• Prior authorization: We coordinate with your doctor for any required approvals
• Ongoing management: We handle renewals and monitor for new savings opportunities
• Refill coordination: We ensure continuous medication supply without gaps

How QuickRx supports patients:

As a specialty pharmacy, QuickRx is reimbursed through normal pharmacy dispensing—we don’t need to charge patients separately for copay assistance services. Our goal is to help as many patients as possible access their Afinitor treatment affordably.

Ready to get started? Call (917) 830-2525 or complete our online form for free Afinitor copay assistance.

Yes, Medicare patients have options for reducing Afinitor costs, though they cannot use manufacturer copay cards due to federal anti-kickback regulations. QuickRx helps Medicare patients navigate alternative assistance programs.

Assistance options for Medicare patients:

• Foundation grants: Independent charitable foundations like PAN Foundation, HealthWell Foundation, and cancer-specific organizations provide grants to help cover medication costs
• State pharmaceutical assistance programs (SPAPs): Some states offer additional prescription assistance for Medicare beneficiaries
• Medicare Extra Help (LIS): Low-income subsidies that reduce Part D costs. Learn more about Medicare prescription drug assistance.
• Novartis Patient Assistance Foundation: May provide free Afinitor to qualifying Medicare patients with limited income

How QuickRx helps Medicare patients:

Our patient navigators understand the specific challenges Medicare patients face with specialty medications. We actively monitor foundation grant openings, help complete applications quickly when funds become available, and explore every option to reduce your out-of-pocket costs for Afinitor.

Call (917) 830-2525 to discuss Medicare assistance options for Afinitor.

Common side effects of Afinitor (everolimus) include stomatitis (mouth sores), infections, fatigue, diarrhea, and rash. Most side effects can be managed with proper supportive care, and your healthcare team will monitor you throughout treatment.

Most common Afinitor side effects:

• Stomatitis (mouth sores): Affects many patients; your doctor may prescribe alcohol-free dexamethasone mouthwash to help prevent or treat. Learn more about managing mouth sores during cancer treatment.
• Infections: Afinitor can lower your immune response, increasing infection risk
• Fatigue: Feeling tired or weak is common during treatment
• Diarrhea: May require dietary changes or medication to manage
• Rash: Skin changes including rash, dry skin, or itching
• Decreased appetite: May lead to weight loss during treatment
• Nausea: Usually manageable with anti-nausea medications

Serious side effects requiring immediate attention:

• Non-infectious pneumonitis: Lung inflammation causing cough, difficulty breathing, or fever
• Severe infections: Signs include fever, chills, or flu-like symptoms
• Kidney problems: Changes in urination or swelling
• Severe mouth sores: That prevent eating or drinking

Contact your healthcare provider immediately if you experience any serious side effects. QuickRx pharmacists are also available at (917) 830-2525 to answer questions about managing Afinitor side effects.

Treatment duration with Afinitor (everolimus) varies based on your specific condition and how well you respond to therapy. Your oncologist or specialist will determine the appropriate treatment length based on your individual circumstances.

General treatment duration guidelines:

• Cancer indications: Treatment typically continues as long as Afinitor is providing benefit and side effects are manageable—this may be months to years depending on response
• TSC-related conditions: Treatment is often long-term to maintain control of tumor growth or angiomyolipomas
• Dose adjustments: Your doctor may adjust your dose based on side effects or response, which can extend treatment duration

Factors affecting treatment length:

Your doctor will consider tumor response, disease progression, side effects, and your overall health when determining how long to continue Afinitor. Regular monitoring through imaging and lab tests helps assess treatment effectiveness.

QuickRx supports long-term treatment:

For patients on extended Afinitor treatment, QuickRx manages ongoing copay assistance renewals, monitors for new savings programs, coordinates refills, and provides continuous support throughout your treatment journey. Our team is here to help for as long as you need Afinitor.

Questions about your treatment plan? Call (917) 830-2525 to speak with a QuickRx patient navigator.

The Novartis Universal Co-Pay Card is a manufacturer-sponsored program that helps eligible commercially insured patients reduce their out-of-pocket costs for Afinitor (everolimus). Eligible patients may pay as little as $0 per prescription.

Eligibility requirements:

• Commercial insurance: Must have private or employer-sponsored health insurance
• Prescription coverage: Your insurance must cover Afinitor (even with a high copay)
• U.S. resident: Must live in the United States
• Age requirement: Typically 18 years or older

Who is NOT eligible:

• Medicare, Medicaid, or other government insurance beneficiaries
• Patients whose insurance does not cover Afinitor
• Cash-paying patients without insurance

How QuickRx helps with the Novartis copay card:

QuickRx handles the entire enrollment process for the Novartis Universal Co-Pay Card. We verify your eligibility, complete the application, and apply the savings directly to your prescription—you don’t have to submit claims or wait for reimbursement.

Call (917) 830-2525 to check your eligibility for the Afinitor copay card.

The Novartis Patient Assistance Foundation is a program that provides free Afinitor (everolimus) to eligible patients who cannot afford their medication. This program is available for uninsured patients and those with limited income.

Eligibility requirements:

• No insurance or inadequate coverage: Patients without prescription coverage or whose insurance denies Afinitor
• Income limits: Must meet certain household income requirements (varies by program)
• U.S. resident: Must live in the United States
• Valid prescription: Must have a prescription from a licensed healthcare provider

What the program provides:

Patients approved for the Novartis Patient Assistance Foundation receive their Afinitor medication at no cost. The medication is typically shipped directly to the patient’s home or doctor’s office.

How QuickRx helps with patient assistance:

QuickRx patient navigators are experienced with the Novartis Patient Assistance Foundation application process. We help gather required documentation, complete applications accurately, and follow up to ensure timely approval. Our goal is to get you enrolled as quickly as possible.

Call (917) 830-2525 to learn more about the Afinitor patient assistance program.

Afinitor (everolimus) works by inhibiting the mTOR (mammalian target of rapamycin) protein, which plays a key role in cell growth, division, and survival. By blocking mTOR, Afinitor helps slow or stop the growth of cancer cells and abnormal cells.

Mechanism of action:

The mTOR protein is part of a signaling pathway that tells cells when to grow and divide. In many cancers and in tuberous sclerosis complex (TSC), this pathway is overactive, leading to uncontrolled cell growth. Afinitor binds to a protein called FKBP-12, and this complex then inhibits mTOR, helping to:

• Slow tumor growth: By reducing signals that tell cancer cells to multiply
• Reduce blood vessel formation: Tumors need new blood vessels to grow; Afinitor can help limit this process
• Shrink existing tumors: In some cases, blocking mTOR can cause tumors to decrease in size

Learn more about targeted cancer therapies from the National Cancer Institute.

Why mTOR inhibition matters:

mTOR inhibitors like Afinitor represent a targeted approach to cancer treatment. Rather than affecting all rapidly dividing cells (like traditional chemotherapy), Afinitor specifically targets the molecular pathway driving tumor growth.

Afinitor (everolimus) can interact with many other medications, so it’s important to tell your doctor and pharmacist about all drugs you take. Some interactions can increase side effects or reduce Afinitor’s effectiveness.

Medications that may interact with Afinitor:

• Strong CYP3A4 inhibitors: Ketoconazole, itraconazole, clarithromycin, ritonavir—may increase Afinitor levels
• Strong CYP3A4 inducers: Rifampin, phenytoin, carbamazepine, St. John’s Wort—may decrease Afinitor effectiveness
• Live vaccines: Should be avoided during Afinitor treatment due to immune suppression
• ACE inhibitors: May increase risk of angioedema when combined with Afinitor

Foods and supplements to avoid:

• Grapefruit and grapefruit juice: Can significantly increase Afinitor levels
• Seville oranges and pomelos: Similar interaction as grapefruit
• St. John’s Wort: May reduce Afinitor effectiveness

How QuickRx helps with drug interactions:

QuickRx pharmacists review your complete medication list to identify potential interactions with Afinitor. We work with your healthcare team to ensure your medications can be taken safely together. Call (917) 830-2525 to speak with a pharmacist about your medications.

Regular lab monitoring is required while taking Afinitor (everolimus) to check for side effects and ensure the medication is working safely. Your healthcare provider will schedule these tests at appropriate intervals.

Common monitoring tests:

• Complete blood count (CBC): To monitor for low blood cell counts
• Blood glucose: Afinitor can raise blood sugar levels
• Lipid panel: Cholesterol and triglycerides may increase during treatment
• Kidney function tests: To monitor for kidney problems
• Liver function tests: To check for liver toxicity

When monitoring typically occurs:

• Before starting treatment: Baseline tests establish your normal values
• During treatment: Usually monthly at first, then less frequently if stable
• With dose changes: Additional monitoring may be needed after adjustments

What to watch for between visits:

Report any new symptoms to your healthcare provider, including signs of infection (fever, chills), breathing problems, mouth sores, or unusual fatigue. Early detection of side effects allows for prompt management.

Questions about monitoring requirements? Call (917) 830-2525 to speak with a QuickRx pharmacist.

Afinitor (everolimus) should NOT be taken during pregnancy, as it can cause harm to an unborn baby. Women who could become pregnant should use effective contraception during treatment and for a period after stopping Afinitor.

Important information for women:

• Pregnancy testing: A negative pregnancy test is required before starting Afinitor
• Contraception during treatment: Use highly effective birth control while taking Afinitor
• After stopping treatment: Continue contraception for at least 8 weeks after your last dose
• Breastfeeding: Do not breastfeed during treatment or for 2 weeks after your last dose

Important information for men:

• Fertility: Afinitor may affect male fertility
• Contraception: Men with female partners who could become pregnant should use effective contraception during treatment and for 4 weeks after the last dose

Learn more about fertility during cancer treatment. Discuss family planning concerns with your healthcare provider before starting Afinitor.

Proper storage of Afinitor (everolimus) helps ensure the medication remains effective throughout your treatment. Follow these storage guidelines carefully.

Storage requirements:

• Temperature: Store at room temperature, 68°F to 77°F (20°C to 25°C)
• Light protection: Keep in the original packaging to protect from light
• Moisture: Store in a dry place; avoid bathrooms with high humidity
• Children and pets: Keep out of reach of children and pets

What to avoid:

• Do not freeze: Freezing can damage the medication
• Avoid heat: Do not store near stoves, radiators, or in hot cars
• Do not remove from blister pack: Until ready to take

Medication disposal:

Do not flush unused Afinitor down the toilet. Ask your pharmacist about proper disposal methods or FDA-approved drug take-back programs. Learn more about safe medication disposal from the FDA.

Questions about storing your Afinitor? Call QuickRx at (917) 830-2525.

QuickRx Specialty Pharmacy provides comprehensive support for patients taking Afinitor (everolimus), combining expert pharmacy services with dedicated copay assistance help. We’re committed to making your treatment as affordable and convenient as possible.

What sets QuickRx apart:

• Free copay assistance: We never charge for enrollment in savings programs—our copay assistance services are always free
• Dedicated patient navigators: Work with the same team members who know your situation
• Expert pharmacists: Specialized in oncology and specialty medications
• Home delivery: Convenient shipping directly to your door
• Refill coordination: We proactively manage your prescription to prevent gaps in therapy
• Insurance advocacy: We handle prior authorizations and insurance issues on your behalf

Our commitment to patients:

QuickRx is a nationwide specialty pharmacy licensed in all 50 states. We understand that managing cancer or TSC is challenging enough without worrying about medication costs. Our team is here to help you access the Afinitor you need at the lowest possible cost.

Ready to get started? Call (917) 830-2525 or (800) 496-6111 to speak with a patient navigator today.

Afinitor, Afinitor Disperz, and Zortress all contain the same active ingredient (everolimus) but are formulated differently for different medical uses. Understanding these differences helps ensure you receive the right medication for your condition.

Afinitor (Standard Tablets):

Afinitor comes as standard tablets that must be swallowed whole with water. These tablets should never be cut, crushed, or chewed as this can affect how the medication is absorbed. Afinitor is used at higher doses (typically 10 mg daily) for cancer treatment including breast cancer, renal cell carcinoma, neuroendocrine tumors, and TSC-related conditions.

Afinitor Disperz (Dispersible Tablets):

Afinitor Disperz is designed for patients who have difficulty swallowing pills. These dispersible tablets can be dissolved in water or placed on the tongue to dissolve. This formulation is particularly useful for pediatric patients or adults with swallowing difficulties. Special handling is required:

• Wear gloves when handling tablets
• Pregnant women should not mix the medication
• Use immediately after mixing—discard any unused portion after 1 hour

Zortress (Transplant Formulation):

Zortress is specifically formulated for organ transplant patients and is used at much lower doses than cancer treatments (typically 0.75 mg twice daily for kidney transplants or 1 mg twice daily for liver transplants). It helps prevent the body from rejecting transplanted organs by suppressing the immune system. Learn more about immunosuppressants for transplant patients.

QuickRx dispenses all three formulations and provides copay assistance for each. Call (917) 830-2525 to discuss which everolimus product you need.

Before starting everolimus treatment, it’s important to share your complete medical history with your healthcare provider. This helps ensure Afinitor is safe for you and allows your doctor to monitor for potential complications.

Current health conditions to discuss:

• Active infections or recent illness: Everolimus suppresses the immune system
• Liver or kidney disease: May require dose adjustments
• Diabetes or blood sugar problems: Afinitor can raise blood sugar levels
• History of hepatitis B infection: May reactivate during treatment
• Planned surgeries or recent wounds: Everolimus can affect wound healing
• Lactose intolerance: Some formulations contain lactose
• Lung or breathing problems: Risk of non-infectious pneumonitis

Pregnancy and fertility considerations:

• Pregnancy status: Pregnancy testing required before starting treatment
• Family planning: Discuss fertility impacts and contraception requirements
• Breastfeeding: Must discontinue breastfeeding during treatment

All medications and supplements:

Bring a complete list of all prescription medications, over-the-counter drugs, vitamins, and herbal supplements. Many products interact with everolimus, including St. John’s Wort and grapefruit products.

QuickRx pharmacists can help review your medication list for potential interactions. Call (917) 830-2525.

If you miss a dose of Afinitor, what you should do depends on how much time has passed since your scheduled dose. Maintaining consistent blood levels of everolimus is important for treatment effectiveness.

For Afinitor and Afinitor Disperz (cancer/TSC treatment):

• Within 6 hours of your usual time: Take the missed dose immediately
• More than 6 hours late: Skip the missed dose and take your next dose at the regular scheduled time
• Never double dose: Do not take two doses at the same time to make up for a missed dose

For Zortress (transplant patients):

• Remember soon after: Take the missed dose as soon as you remember
• Close to next dose: If it’s almost time for your next dose, skip the missed dose
• Never double dose: Do not take two doses at the same time

Tips to avoid missing doses:

• Take your medication at the same time every day
• Use a pill organizer or medication reminder app
• Set daily alarms on your phone
• Keep your medication in a visible location (away from children)

If you frequently miss doses or have questions about your dosing schedule, contact your healthcare provider or call QuickRx at (917) 830-2525.

Yes! QuickRx dispenses Zortress (everolimus) and provides free copay assistance services for organ transplant patients. We understand the critical importance of continuous immunosuppressant therapy after kidney or liver transplantation.

Zortress copay assistance options:

• Novartis copay card: Eligible commercially insured patients may significantly reduce out-of-pocket costs
• Patient assistance programs: For uninsured or underinsured transplant patients
• Transplant-specific foundations: Organizations like the American Kidney Fund and National Kidney Foundation may offer grants

Why transplant patients choose QuickRx:

• Specialty expertise: Our pharmacists understand transplant medication protocols
• Coordination with transplant teams: We work directly with your transplant center
• No gaps in therapy: Proactive refill management ensures continuous medication supply
• Drug interaction monitoring: We review all your transplant medications together
• Home delivery: Convenient nationwide shipping

Zortress dosing for transplant patients:

Zortress is typically dosed at 0.75 mg twice daily for kidney transplants or 1 mg twice daily for liver transplants, taken at the same time as cyclosporine or tacrolimus. Your transplant team will determine your specific dose based on blood levels and response.

Need Zortress copay assistance? Call (917) 830-2525 or (800) 496-6111 to speak with a QuickRx transplant specialist.