What to know about Xgeva (Denosumab) for Prostate Cancer

Common Side Effects

These may occur in more than 1 in 10 patients:

• Low calcium levels (hypocalcemia) – may cause muscle cramps, tingling, or confusion

• Fatigue

• Nausea

• Diarrhea

• Back pain

• Joint or muscle pain

• Headache

• Shortness of breath

• Pain in the arms or legs

Less Common but Notable Side Effects

Occurring in fewer patients but still important to monitor:

• Constipation

• Vomiting

• Loss of appetite

• Swelling in the hands or feet

• Skin rash or itching

• Increased risk of infections (e.g., bladder infections or skin infections)

• Anemia (low red blood cell count)

Serious or Rare Side Effects

These are uncommon but may be severe and require urgent care:

• Osteonecrosis of the jaw (ONJ): A serious condition where the jawbone begins to die. Signs include jaw pain, loose teeth, swelling, or exposed bone.

• Atypical femur fractures: Rare thigh bone fractures that can occur with little or no trauma. Pain in the groin or thigh may be an early sign.

• Severe hypocalcemia: Especially in patients with kidney problems or vitamin D deficiency. Symptoms include muscle spasms, seizures, and abnormal heart rhythms.

• Serious infections: Including cellulitis, pneumonia, or urinary tract infections.

• Allergic reactions: Swelling of the face, lips, or tongue, trouble breathing, or hives require immediate medical attention.

Lab Abnormalities That May Appear Without Symptoms

Your healthcare provider may monitor:

• Calcium, phosphorus, and magnesium levels – as these may drop during treatment

• Creatinine – to assess kidney function

• Parathyroid hormone (PTH) – may increase in response to low calcium

What to Do If You Experience Side Effects

• Mild symptoms: Like nausea or fatigue, are often temporary. Stay hydrated, rest, and consult your healthcare provider if they persist.

• Signs of low calcium: (muscle spasms, confusion, numbness) – report immediately.

• Jaw pain or dental issues: Notify your doctor before any dental procedures. Good oral hygiene and regular dental checkups are essential.

• Signs of infection: (fever, chills, redness, or swelling) – contact your provider promptly.

Xgeva (Denosumab) Copay Assistance comes in the form of various savings programs, which are often referred to as “Xgeva or Denosumab copay cards.” These patient assistance programs can be very difficult for patients to find, enroll, and keep an active status. QuickRx will be there to guide you through it all.
Although these programs are free, many people are not aware they exist. That is where QuickRx comes in. We have a highly-skilled team dedicated to helping make prescription copays affordable for all who qualify by facilitating access to these programs.

You’ll never have to worry about jumping through hoops or wasting hours ever again. Each copay assistance program has their own set of rules and regulations. This is the part of the process that has proven to be frustrating for many people seeking copay assistance.

However, with QuickRx your experience will be anything but difficult. Our dedicated team will work to make the Xgeva (Denosumab) Copay Card process as seamless as possible for you. In fact, your part of the process involves just a few short, easy steps to find out if you qualify for copay assistance. Fill out the form above this section and someone from our amazing pharmacy team will contact you within 1-2 business days.

Step 1:
Get started using one of these options;

• You can call us at (917) 830-2525 or toll-free at (800)-496-6111.
• You can also fill out our Contact Form and someone will call you back within 1-2 business days.

Step 2:
Fill out some easy forms

Step 3:
Submit a few pieces of documentation to our team.

That’s it! From there, our team will help you find out if you qualify. If you meet the qualification guidelines, our team will ensure that your discounts are automatically applied for you at the pharmacy, coordinate pickup or home delivery of your medications, and they’ll even continue to monitor your case! With QuickRx you will have peace of mind knowing that you will never have any surprise lapse in copay assistance benefits.