Apply for Lupron (Leuprolide) Copay Assistance Now

We believe that high deductibles and copays shouldn’t prevent anyone from receiving the medications they need. That’s why at QuickRx, we offer assistance accessing Copay Assistance Programs. This is designed to help patients reduce their monthly out-of-pocket costs.

Our program partners with many foundations and manufacturer assistance programs to help make medication affordable. Fill out the form on this page and someone from our dedicated team will be in touch within one business day. 

Worried that copay assistance might not be for you? Give us a call! Not only are we dedicated to helping with access to copay assistance programs, but we are also committed to giving every person their lowest price possible, even if you aren’t using prescription coverage.

Yes, QuickRx provides completely free enrollment support for Lupron copay cards and patient assistance programs. We never charge service fees. The copay card itself is also free from the manufacturer for eligible patients with commercial insurance and may significantly reduce your out-of-pocket costs. Patient assistance programs for eligible uninsured or underinsured patients may provide Lupron at reduced or no cost. We handle all applications and paperwork at no cost to you.

Eligibility depends on your insurance type. For the Lupron manufacturer copay card, you typically need commercial or private insurance (not government insurance programs). For patient assistance programs, you may qualify if you’re uninsured, underinsured, or meet certain eligibility requirements.

QuickRx reviews your insurance and situation to determine which programs you may qualify for. Contact us at (917) 830-2525 for a free eligibility assessment specific to your situation.

Getting a Lupron copay card through QuickRx is simple:

1. Contact QuickRx: Call (917) 830-2525 or complete our online enrollment form
2. Provide Information: We’ll need your insurance details and prescription information
3. We Apply: QuickRx handles all copay card applications and paperwork
4. Get Approved: Most patients receive approval within 24-48 hours
5. Start Saving: Your copay discount applies automatically when filling prescriptions through QuickRx

Our pharmacy team manages the entire process, so you don’t have to navigate manufacturer websites or insurance requirements on your own.

Medicare patients cannot use manufacturer copay cards due to federal regulations. However, Medicare does cover Lupron, and QuickRx can help eligible Medicare patients explore alternative assistance options. Coverage and out-of-pocket costs vary by plan. Contact QuickRx at (917) 830-2525 to discuss your specific Medicare coverage and potential assistance options.

Manufacturer copay cards can often be activated within 24-48 hours for eligible commercially insured patients. Other assistance programs may take longer depending on documentation requirements and program availability. At QuickRx, we expedite this process by pre-verifying your information and submitting complete applications. For patients with urgent medication needs, we work to identify solutions to prevent gaps in treatment while waiting for program approval.

Lupron (leuprolide acetate) is an FDA-approved gonadotropin-releasing hormone (GnRH) agonist used to treat several conditions:

• Prostate cancer, advanced: Treatment of advanced prostate cancer
• Endometriosis: Management of endometriosis for pain relief and reduction of endometriotic lesions
• Uterine fibroids: Preoperative hematologic improvement of patients with anemia caused by fibroids (used in combination with iron)
• Central precocious puberty: Treatment of pediatric patients with central precocious puberty

For more information about leuprolide, visit the National Library of Medicine.

Leuprolide is an agonist of gonadotropin releasing hormone (GnRH) receptors. It produces an initial increase in luteinizing hormone (LH) and follicle stimulating hormone (FSH), which leads to a transient increase in testosterone (in males) and estrogen (in females). With continuous administration, leuprolide then results in suppression of ovarian and testicular steroidogenesis due to decreased levels of LH and FSH. In males, testosterone levels are reduced to below castrate levels. Testosterone suppression occurs in approximately 2 to 4 weeks of continued therapy.

Leuprolide is available in several brand formulations:

• Lupron Depot: Intramuscular injection available in 1-month (7.5 mg), 3-month (22.5 mg), 4-month (30 mg), and 6-month (45 mg) formulations
• Lupron Depot-Ped: Formulation specifically for pediatric central precocious puberty (1-month, 3-month, and 6-month)
• Eligard: Subcutaneous injection available in 1-month, 3-month, 4-month, and 6-month formulations
• Fensolvi: Subcutaneous 6-month formulation for central precocious puberty
• Camcevi: Subcutaneous prefilled syringe for prostate cancer (6-month)
• Lutrate Depot, Vabrinty: Additional depot formulations

Your healthcare provider will determine the most appropriate formulation and dosing schedule based on your condition.

Lupron administration depends on the formulation:

• Lupron Depot: Administered by a healthcare provider as a single intramuscular injection into the gluteal area, anterior thigh, or deltoid. Injection site should be alternated. Must be administered within 2 hours of preparation.
• Eligard: Subcutaneous injection. Vary or rotate injection site; choose site with adequate subcutaneous tissue that does not have excessive pigment, nodules, lesions, or hair. Must be administered within 30 minutes of preparation.
• Camcevi: Subcutaneous injection in the upper or mid abdominal area.

Most patients receive injections at their healthcare provider’s office. QuickRx can coordinate nursing support for patients who require in-home injection assistance.

Common side effects of leuprolide include:

• Hot flashes (very common)
• Injection site reactions (bruising, discomfort, erythema, pain, swelling)
• Headache
• Fatigue and weakness
• Mood changes and emotional lability
• Decreased libido
• Sweating (diaphoresis)
• Nausea and vomiting
• Musculoskeletal pain
• Insomnia

For complete safety information, consult your healthcare provider and review the FDA prescribing information at FDA.gov.

Serious warnings and precautions for leuprolide include:

• Cardiovascular risk: A higher chance of heart attack, stroke, or sudden heart death has been noted when drugs like this were used in males
• QT prolongation: Lowering male hormones in the body may raise the chance of a type of heartbeat that is not normal called prolonged QT interval
• Tumor flare: Symptoms may get worse during the first few weeks after starting treatment. Cases of paralysis and even death have happened in some people with advanced prostate cancer
• Bone density loss: This drug may cause weak bones, especially with long-term use
• High blood sugar: New or worsening diabetes may occur
• Pituitary apoplexy: A rare but serious pituitary gland problem, usually within 2 weeks after the first dose

Report any concerning symptoms to your healthcare provider immediately.

Generic leuprolide acetate injection is available for some formulations. However, the long-acting depot formulations require specialized microsphere technology. Brand formulations include Lupron Depot, Eligard, Fensolvi, Camcevi, Lutrate Depot, and Vabrinty, each with unique release characteristics. Do not use a fractional dose of the 3-, 4-, or 6-month depot formulation, or a combination of doses of the monthly depot formulation or any depot formulation due to different release characteristics.

Before starting leuprolide, tell your healthcare provider about:

• If you are allergic to this drug, GnRH, GnRH-agonist analogs, or any component of the formulation
• If you have unexplained vaginal bleeding (females)
• If you are pregnant, may be pregnant, or breastfeeding — leuprolide is contraindicated in pregnancy and may cause fetal harm
• If you have bladder blockage or growths on or near the spine or spinal cord (males)
• History of heart disease, diabetes, or depression
• All medications you are taking

Your healthcare provider will monitor your bone mineral density, blood glucose, and cardiovascular health during treatment.

Leuprolide suppresses ovarian and testicular steroidogenesis. Decreased libido, impotence, erectile dysfunction, and menstrual disorders may result, and fertility may be impaired. However, suppression of fertility is reversible following discontinuation of leuprolide. Pregnancy rates are not expected to be affected once leuprolide is discontinued. Most of the time, this drug stops menstrual bleeding in females — this is not a method of birth control. A nonhormonal contraceptive should be used during leuprolide therapy if contraception is needed.

Treatment duration depends on your condition:

• Prostate cancer: Treatment is usually continued, including after development of metastatic (castration-resistant) disease
• Endometriosis: Initial treatment maximum 6 months as monotherapy or with add-back therapy. Total duration of therapy should not exceed 12 months
• Uterine fibroids: Up to 3 months preoperatively (in combination with iron)
• Central precocious puberty: Continued until the appropriate age for the onset of puberty; therapy is typically discontinued at approximately 10 to 12 years of age

Your healthcare provider will determine the appropriate treatment duration based on your individual situation.

Yes. QuickRx Specialty Pharmacy is licensed in all 50 states and can dispense Lupron (leuprolide acetate) with home delivery nationwide. We provide free copay assistance enrollment for all eligible patients regardless of location. Our services include benefits verification, manufacturer copay card enrollment, patient assistance program applications, prior authorization support, and ongoing benefits monitoring. Contact us at (917) 830-2525 or toll-free at (800) 496-6111 to get started.

The medical information on this page is based on peer-reviewed clinical literature and authoritative drug references:

• Leuprolide. Lexidrug. UpToDate, Inc. Accessed November 2025. UpToDate
• Lupron Depot (leuprolide acetate) [prescribing information]. North Chicago, IL: AbbVie Inc. FDA Drug Label
• Leuprolide. StatPearls [Internet]. National Center for Biotechnology Information. NCBI Bookshelf
• National Cancer Institute. Prostate Cancer Treatment. NCI
• American College of Obstetricians and Gynecologists. Endometriosis. ACOG

Medical Disclaimer: This page provides educational information about Lupron (leuprolide acetate) copay assistance programs and is not intended as medical advice. All medical decisions should be made in consultation with your qualified healthcare provider. QuickRx Specialty Pharmacy does not guarantee approval or specific savings amounts, which depend on individual eligibility criteria.