Need Jynarque (Tolvaptan) Copay Assistance?

Yes! Our Jynarque (Tolvaptan) copay assistance program is 100% free for everyone. We will never charge any fees for helping you lower the cost of your copays. Fill out the form on this page to get started.

Jynarque can be expensive, and many patients seek financial assistance. There are patient assistance programs and co-pay cards to help reduce the cost of the medication, but often these programs can be hard to identify and navigate, making affordable copays seemingly impossible.

This is where QuickRx comes in. Our dedicated team will take care of all the hard parts for you. All you need to do to get started is fill out the form on this page or give us a call at (347) 691-3494

Common Side Effects of Jynarque:

1. Thirst and Increased Urination: One of the most commonly reported side effects of Jynarque is increased thirst (polydipsia) and more frequent urination (polyuria). These effects are often mild to moderate and tend to occur shortly after starting the medication.
2. Elevated Liver Enzymes: Jynarque can sometimes lead to elevated liver enzymes, which may be detected through blood tests. Regular monitoring by your healthcare provider is essential to ensure your liver function remains within a safe range.
3. Dehydration: Some individuals may experience dehydration while taking Jynarque. Symptoms of dehydration can include dry mouth, dark urine, and dizziness. It’s important to stay well-hydrated and consult your healthcare provider if you notice signs of dehydration.
4. Increased Urination at Night: Nocturia, or increased urination at night, can be a side effect of Jynarque. This may disrupt your sleep patterns, so it’s advisable to discuss any sleep-related concerns with your healthcare provider.

Common Drug Interactions with Jynarque:

1. CYP3A4 Inhibitors: Jynarque is metabolized by the enzyme CYP3A4 in the liver. Medications that inhibit CYP3A4 activity can increase the levels of Jynarque in your bloodstream, potentially leading to a higher risk of side effects. Some common CYP3A4 inhibitors include certain antifungal medications, protease inhibitors used in HIV treatment, and some antibiotics. It’s crucial to inform your healthcare provider of all the medications you are taking to assess any potential interactions.
2. CYP3A4 Inducers: On the other hand, medications that induce CYP3A4 activity may decrease the effectiveness of Jynarque. These inducers can lead to lower Jynarque levels in your body, reducing its ability to slow the progression of ADPKD. Rifampin, a medication used to treat tuberculosis, is an example of a CYP3A4 inducer. Your healthcare provider will need to monitor your condition closely if you are taking both Jynarque and a CYP3A4 inducer.
3. Grapefruit and Grapefruit Juice: Grapefruit and grapefruit juice contain compounds that can interfere with the metabolism of various medications, including Jynarque. Avoid consuming grapefruit or its derivatives while taking Jynarque to prevent potential interactions.
4. Other Medications: While the above categories cover some common interactions, it’s essential to discuss all your medications, including over-the-counter drugs and supplements, with your healthcare provider. They can provide personalized guidance based on your specific medication regimen.

Jynarque can help slow the progression of kidney disease in ADPKD patients, potentially preserving kidney function and delaying the need for kidney transplantation or dialysis.

Seek emergency medical attention or call the Poison Help line immediately at 1-800-222-1222.