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Gilenya (Fingolimod) is an immunosuppressant. It works by keeping immune cells trapped in your lymph nodes so they can’t reach the central nervous system (brain and spinal cord).
Gilenya is used to treat relapsing multiple sclerosis (MS) in adults, and children and adolescents aged 10 years and older.
Gilenya will not cure MS, it will only decrease the frequency of relapse symptoms.
Another brand name is Tascenso ODT, which stands for “Orally Disintegrating Tablet.” This refers to the fact that this version of Fingolimod melts on the tongue and does not need to be swallowed.
In adults and pediatric patients 10 years of age and older weighing more than 40 kg, the recommended dosage of Gilenya is 0.5 mg orally once-daily.
In pediatric patients 10 years of age and older weighing less than or equal to 40 kg, the recommended dosage of Gilenya is 0.25 mg orally once daily.
Fingolimod doses higher than 0.5 mg are associated with a greater incidence of adverse reactions without additional benefit.
These may occur in more than 1 in 10 patients:
Headache
Flu
Diarrhea
Back pain
Cough
Increased liver enzymes (ALT, AST)
Abdominal pain
Fatigue
Depression
Sinusitis
Pain in extremities
Dizziness
Upper respiratory tract infections (cold, sinusitis)
Bronchitis
Herpes virus infections (cold sores, shingles)
Fungal infections
Urinary tract infections
Pneumonia (rare but serious)
Note: Fingolimod increases the risk of serious infections, including progressive multifocal leukoencephalopathy (PML), a rare and often fatal brain infection.
Especially around the time of first dose:
Bradycardia (slow heart rate)
Atrioventricular (AV) block
Palpitations
Hypotension
Fainting or dizziness due to slowed heart rate
Monitoring required: First-dose observation with ECG monitoring for at least 6 hours is recommended.
Macular edema (swelling of the retina):
Blurred vision
Shadows or blind spots
Decreased visual acuity
Most likely to occur within 3-4 months of treatment
Risk increases in patients with diabetes or history of uveitis. An eye exam is recommended before starting and again after 3–4 months.
Elevated liver enzymes (ALT, AST, GGT, bilirubin)
Hepatotoxicity
Lymphopenia (low lymphocyte count)
Leukopenia (low white blood cell count)
Thrombocytopenia (low platelet count)
Headache
Migraine
Dizziness
Depression
Anxiety
Insomnia
Seizures (rare but reported)
Suicidal thoughts or behavior (rare, monitor in those with history of depression)
Shortness of breath (dyspnea)
Cough
Decrease in lung function (reduced FEV1)
Rare: interstitial lung disease
Rash
Eczema
Alopecia (hair thinning or loss)
Pruritus (itching)
Progressive multifocal leukoencephalopathy (PML) – life-threatening brain infection
Posterior reversible encephalopathy syndrome (PRES) – a rare neurological disorder
Severe liver injury
Melanoma – increased risk of skin cancer
Basal cell carcinoma – monitor skin regularly
Hemophagocytic lymphohistiocytosis (HLH) – a life-threatening immune overactivation syndrome
Rebound MS disease activity after stopping fingolimod—can be severe or life-threatening
Pregnancy Category X: Teratogenic in animals—contraindicated in pregnancy
Women of childbearing potential should use effective contraception during and for 2 months after stopping treatment
While it is not possible to determine what your copay cost or cash price will be for Gilenya or its generic counterpart Fingolimod, calling our pharmacy team or filling out the form above will be the best way to get the fastest answers.
We believe that high deductibles and copays shouldn’t prevent anyone from receiving the medications they need. That’s why at QuickRx, we offer a Movement Disorder Copay Assistance Program that includes Gilenya Copay Assistance.
This is designed to help patients reduce their copays and out-of-pocket costs for their medication. Our program partners with various foundations and manufacturer assistance programs to help make a patient’s medication affordable.
Here are the ways to apply for the Gilenya (Fingolimod) Copay Assistance program:
Gilenya is an immunosuppressant. It works by keeping immune cells trapped in your lymph nodes so they can’t reach the central nervous system (brain and spinal cord).
Gilenya and its generic Fingolimod are both produced as a capsule.
Gilenya (Fingolimod) should be taken orally (by mouth) with water.
Call your doctor for instructions. If you miss 1 or more doses, you may need to take your next dose under medical observation in a medical setting.
Gilenya (Fingolimod) is a medication prescribed for Multiple Sclerosis. It works by reducing the number of certain immune cells in the body that can attack the nervous system in MS. By modulating the immune response, Gilenya helps reduce the frequency of MS relapses and slows down the progression of the disease.
Gilenya is approved for the treatment of relapsing forms of MS, including relapsing-remitting MS (RRMS) and active secondary progressive MS (SPMS) in some countries. It is not indicated for primary progressive MS.