FAQs: Abiraterone and Zytiga

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How Long Does it take Zytiga to lower PSA?

The time it takes for Zytiga (also commonly referred to as its generic, Abiraterone Acetate) to lower PSA levels can vary depending on the individual and the extent of their disease. In clinical trials, significant PSA reductions were observed as early as two weeks after starting Zytiga treatment, with maximum reductions typically occurring within the first few months of treatment. 

However, it is important to note that PSA levels may not be the best indicator of treatment response, as some patients may continue to have rising PSA levels despite experiencing clinical benefit from Zytiga. Your healthcare provider will monitor your PSA levels and other factors to assess the effectiveness of your treatment.  

How Long does Zytiga work?

The duration of effectiveness of Zytiga (Abiraterone Acetate) can vary depending on the individual and the extent of their disease. In clinical trials, patients treated with Zytiga in combination with prednisone showed improved overall survival and progression-free survival compared to those receiving placebo. 

In general, the effectiveness of Zytiga may decrease over time as the cancer cells develop resistance to the treatment. However, in some cases, the medication can continue to be effective for an extended period of time. Your healthcare provider will monitor your response to treatment and may adjust your medication dose or switch to a different treatment if necessary. 

It is important to note that Zytiga is not a cure for advanced prostate cancer, but it can help slow the progression of the disease and improve quality of life for some patients. Your healthcare provider can provide more information on what to expect from Zytiga treatment and how long it may be effective for you. 

Zytiga and Coffee: Do They go together? 

Yes, you can take Zytiga (Abiraterone Acetate) with coffee. There are no known interactions between Zytiga and coffee or caffeine. However, it is recommended to take Zytiga on an empty stomach, at least one hour before or two hours after eating. This is because food can decrease the absorption of Zytiga, which can make it less effective. 

If you prefer to have your coffee with breakfast or a meal, it is recommended to take Zytiga at a different time of day when your stomach is empty. You should also avoid drinking grapefruit juice or eating grapefruit while taking Zytiga, as it can increase the levels of the medication in your body and lead to potential side effects. It is important to follow your healthcare provider’s instructions on how to take Zytiga and any other medications you are taking.

What is the Cost of Zytiga?

The cost of Zytiga (Abiraterone Acetate) can vary depending on a number of factors, including your location, the dosage prescribed, and whether you have insurance coverage. 

In the United States, the average wholesale price (AWP) of Zytiga 250 mg tablets is nearly $5,000.00 for a one-month supply. However, the actual cost paid by patients can be lower due to discounts and rebates negotiated by insurance providers and pharmacy benefit managers. It is also important to note that this is the price for the name brand version of this medication.

Meanwhile its generic equivalent, Abiraterone Acetate, is available at QuickRx for $181.20 for a one-month supply of 250mg tablets taken four times per day (120 tablets in total). In addition to this much lower price point, QuickRx representatives will work hard to get you additional savings through our patient assistance programs. These programs can provide financial assistance to eligible patients who meet certain criteria. Your pharmacist can provide more information on how to access these programs, or you can start the process by filling out our application form. 


Can I buy Abiraterone 250mg online? What about buying Abiraterone 500mg online?

Well, technically no and technically yes. Allow us to explain; Abiraterone is a medication for which you need a prescription and must remain under the constant care of your prescriber. Therefore, it is not possible or legal to buy Abiraterone 250mg online or Abiraterone 500mg online as if ordering from Amazon. We strongly caution against ordering any prescription medications online as their formula is not guaranteed and, worst case scenario they could be completely ineffective or they could cause you harm.

However, with QuickRx it is possible to have your doctor submit prescriptions and for you to request refills right on our website. In addition, with nationwide 2-day delivery you will never have to worry about making it into the pharmacy again. It’s a win-win! 

What Happens when Abiraterone stops working?

Like any cancer treatment, Abiraterone may stop working for some patients over time. This may occur due to several reasons, such as the cancer developing resistance to the medication or the cancer progressing despite treatment. 

If Abiraterone stops working, your doctor may recommend other treatment options, such as: 

  1. Chemotherapy: Chemotherapy is a type of cancer treatment that uses drugs to kill cancer cells. It may be recommended if Abiraterone is no longer effective. 
  2. Immunotherapy: Immunotherapy is a type of cancer treatment that helps your immune system fight cancer cells. It may be an option if other treatments are not working. 
  3. Hormone therapy: Hormone therapy is a type of cancer treatment that blocks the production of testosterone or other hormones that may fuel cancer growth. 
  4. Clinical trials: Your doctor may recommend enrolling in a clinical trial to try new treatments that are not yet widely available. 

It’s important to discuss with your doctor any concerns you may have about the effectiveness of your current treatment and explore other options that may be available. 


Is Abiraterone Acetate covered by Medicare?

Abiraterone Acetate is generally covered by Medicare, but the coverage may vary depending on the specific Medicare plan and the individual’s circumstances. 

Abiraterone Acetate is listed as a Medicare Part B drug, which means it is covered under the Medicare medical insurance benefit. However, the specific coverage and cost-sharing for Part B drugs can depend on factors such as the specific plan, the individual’s medical needs, and whether the drug is administered in a doctor’s office or a hospital outpatient setting. 

In addition, some individuals with Medicare may also have prescription drug coverage through a Medicare Part D plan, which may cover the cost of Abiraterone Acetate as well. 

It’s always a good idea to check with your Medicare plan provider or healthcare provider to understand your specific coverage and any potential out-of-pocket costs for Abiraterone Acetate or any other medications. 

Does Medicare pay for Zytiga brand, or just generic Abiraterone Acetate?

While Generic is preferred and will definitely cost a lot less, there are rare occasions where a person may experience differences in the effectiveness of a generic drug and may have a medical need for the brand name. Again, this is incredibly rare. However, if that need should arise your doctor may need to explain that to Medicare or your primary insurance provider to justify medical necessity for Zytiga brand and will indicate the need for brand on your prescription.  

This may be a lengthy process and, in all honesty, is one you want to avoid unless absolutely 100% necessary. If you have any reservations about taking a generic vs. a brand name medication please consult with one of our pharmacists and they will be glad to put your mind at ease.   

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